Description
Melanotan 1 (MT1 / afamelanotide) is a melanocortin-receptor research peptide used in controlled in-vitro studies of receptor pharmacology, second-messenger signalling, and structure–activity relationships under non-clinical laboratory conditions.
Melanotan 1 (MT1 / Afamelanotide) — 10 mg | Research Use Only
This α-MSH analogue incorporates Nle4 and D-Phe7 substitutions (NDP-α-MSH), making it a useful tool for exploring melanocortin receptor engagement and downstream pathways in model systems.
For laboratory research only. Not for human use.
Key features
- α-MSH analogue (NDP-α-MSH) for in-vitro receptor-signalling and SAR studies.
- Supplied as a lyophilised solid for stability and straightforward storage.
- Unit size: 10 mg per vial.
- Each batch released after stringent internal quality checks.
Specifications for Melanotan 1

- Product name: Melanotan 1
- Synonyms: MT1; Afamelanotide; NDP-α-MSH; Nle4,D-Phe7-α-MSH
- Sequence (one-letter): Ac-S-Y-S-Nle-E-H-DF-R-W-G-K-P-V-NH2
- Class: Melanocortin peptide (α-MSH analogue)
- CAS (reference): 75921-69-6
- Form: Lyophilised powder
- Appearance: White to off-white solid
- Note: Counter-ion/hydration state may vary. Refer to the vial label for lot-specific details.
Handling & storage of Melanotan 1
- Storage (dry): Keep vials at 2–8 °C, protected from light and moisture.
- Reconstitution: For step-by-step guidance, see our internal guide:
Reconstituting & Storage. - After reconstitution: Store at 2–8 °C, protect from light, use aliquots to reduce handling, and avoid repeated temperature cycling.
- Compatibility: Use only within research protocols that follow your lab’s SOPs and local regulations.
Looking for complementary materials? See
Bacteriostatic Water 10 ml and related melanocortin research peptides such as
PT-141 (Bremelanotide) 10 mg and
Melanotan II (MT-2) 10 mg.
About Melanotan 1 in research
Researchers use Melanotan 1 to interrogate melanocortin receptor subtype engagement, quantify downstream second-messenger responses, and compare potency/selectivity within the α-MSH family. These studies focus on receptor pharmacology and assay readouts exclusively in controlled, non-clinical in-vitro environments.
Synthesis & quality
Manufactured via controlled, validated peptide-synthesis processes to deliver high purity and lot-to-lot consistency. Each batch undergoes identity, purity, and appearance checks before release.
Legal & safety
XL Peptides supplies materials strictly for laboratory research. Products are not medications, foods, supplements, or cosmetics; not for human or veterinary use. By purchasing, you confirm you are a qualified researcher and will handle the material in line with your institution’s policies and applicable laws.
FAQs about Melanotan 1
What is Melanotan 1?
A melanocortin research peptide (afamelanotide / NDP-α-MSH) used to study receptor signalling and SAR in vitro.
How should I store the peptide?
Keep lyophilised vials at 2–8 °C away from light and moisture. After reconstitution, store at 2–8 °C, protect from light, and avoid repeated temperature cycling.
Where can I find reconstitution guidance?
See our step-by-step internal guide:
Reconstituting & Storage.
Is this product for human use?
No. This material is for research only and is not intended for human consumption or clinical applications.
External resources for researchers
Related research peptides









Reviews
There are no reviews yet.